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1

Toxicity of methylsulfonylmethane in rats

K Horváth, P.E Noker, S Somfai-Relle, R Glávits, I Financsek, A.G Schauss

Journal:

Food and Chemical Toxicology

Year:

2002

Language:

english

File:

PDF, 86 KB

english, 2002

2

Preclinical pharmacokinetics, metabolism, and toxicity of azurin-p28 (NSC745104) a peptide inhibitor of p53 ubiquitination

Lee Jia, Gregory S. Gorman, Lori U. Coward, Patricia E. Noker, David McCormick, Thomas L. Horn, J. Brooks Harder, Miguel Muzzio, Bellur Prabhakar, Balaji Ganesh, Tapas K. Das Gupta, Craig W. Beattie

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 452 KB

english, 2011

3

P62 In vitro bioavailability testing of GGTI-2418 using the Caco-2 model

M. Roberts, L. Coward, P. Noker, L. Jia

Journal:

European Journal of Cancer Supplements

Year:

2007

Language:

english

File:

PDF, 54 KB

english, 2007

4

Secondary Screening System for Preclinical Testing of Human Lung Cancer Therapies

Mulvin, D. W., Howard, R. B., Mitchell, D. H., Noker, P. E., Kruse, C. A., Chu, H. D., Bunn, P. A., Johnston, M. R.

Journal:

JNCI Journal of the National Cancer Institute

Year:

1992

Language:

english

File:

PDF, 5.63 MB

english, 1992

5

P28—The effect of colesevelam hydrochloride on the elimination of potassium perfluorooctanoate (PFOA) from serum in male and female cynomolgus monkeys

David J. Ehresman, Patrick E. Noker, Larry R. Zobel, Geary W. Olsen, Shu-Ching Chang, John L. Butenhoff

Journal:

Reproductive Toxicology

Year:

2012

Language:

english

File:

PDF, 54 KB

english, 2012

6

The biochemical toxicology of methanol

Tephly, T.R., Eells, J.T., Makar, A.B., Noker, P.E., Black, K.A.

Journal:

Toxicology Letters

Year:

1983

Language:

english

File:

PDF, 111 KB

english, 1983

7

Disposition of sucrose octa-isobutyrate in rats, dogs and monkeys

Noker, P.E., Kalin, J.R., McCarthy, D.J., El Dareer, S.M., Chappel, C.I.

Journal:

Food and Chemical Toxicology

Year:

1986

Language:

english

File:

PDF, 533 KB

english, 1986

8

Pharmacokinetics and pharmacodynamics of Phor21-βCG(ala), a lytic peptide conjugate

Lee Jia, Patricia E. Noker, Gary A. Piazza, Carola Leuschner, William Hansel, Gregory S. Gorman, Lori U. Coward, Joseph Tomaszewski

Journal:

Journal of Pharmacy and Pharmacology

Year:

2008

Language:

english

File:

PDF, 213 KB

english, 2008

9

Identifying the safety profile of a novel infectivity-enhanced conditionally replicative adenovirus, Ad5-Δ24-RGD, in anticipation of a phase I trial for recurrent ovarian cancer

John G. Page, Baohong Tian, Karen Schweikart, Joseph Tomaszewski, Ray Harris, Trevor Broadt, Judith Polley-Nelson, Patricia E. Noker, Minghui Wang, Sharmila Makhija, Rose Aurigemma, David T. Curiel, R

Journal:

American Journal of Obstetrics and Gynecology

Year:

2007

Language:

english

File:

PDF, 245 KB

english, 2007

10

Comparative pharmacokinetics of perfluorooctanesulfonate (PFOS) in rats, mice, and monkeys

Shu-Ching Chang, Patricia E. Noker, Gregory S. Gorman, Sheila J. Gibson, Jill A. Hart, David J. Ehresman, John L. Butenhoff

Journal:

Reproductive Toxicology

Year:

2012

Language:

english

File:

PDF, 1.51 MB

english, 2012

11

Variability of tumor response to chemotherapy I. Contribution of host heterogeneity

L. Simpson-Herren, P. E. Noker, S. D. Wagoner

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1987

Language:

english

File:

PDF, 874 KB

english, 1987

12

Distribution of nitroimidazoles and L-phenylalanine mustard in mammary adenocarcinoma 16/C tumors

P. E. Noker, L. Simpson-Herren, S. D. Wagoner

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1987

Language:

english

File:

PDF, 547 KB

english, 1987

13

Simultaneous estimation of pharmacokinetic properties in mice of three anti-tubercular ethambutol analogs obtained from combinatorial lead optimization

Lee Jia, Joseph E. Tomaszewski, Patricia E. Noker, Gregory S. Gorman, Elizabeth Glaze, Marina Protopopova

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2005

Language:

english

File:

PDF, 324 KB

english, 2005

14

Pharmacodynamics and pharmacokinetics of SQ109, a new diamine-based antitubercular drug

Lee Jia, Joseph E Tomaszewski, Colleen Hanrahan, Lori Coward, Patricia Noker, Gregory Gorman, Boris Nikonenko, Marina Protopopova

Journal:

British Journal of Pharmacology

Year:

2005

Language:

english

File:

PDF, 198 KB

english, 2005

15

Comparative pharmacokinetics of perfluorohexanesulfonate (PFHxS) in rats, mice, and monkeys

Maria Sundström, Shu-Ching Chang, Patricia E. Noker, Gregory S. Gorman, Jill A. Hart, David J. Ehresman, Åke Bergman, John L. Butenhoff

Journal:

Reproductive Toxicology

Year:

2012

Language:

english

File:

PDF, 1.02 MB

english, 2012

16

Biodistribution of radiolabeled lipid–DNA complexes and DNA in mice

Ralph Niven, Rodney Pearlman, Todd Wedeking, Jeff Mackeigan, Pat Noker, Linda Simpson-Herren, Janet G. Smith

Journal:

Journal of Pharmaceutical Sciences

Year:

1998

Language:

english

File:

PDF, 174 KB

english, 1998

17

Quantitative determination of apogossypol, a pro-apoptotic analog of gossypol, in mouse plasma using LC/MS/MS

L. Coward, G. Gorman, P. Noker, C. Kerstner-Wood, M. Pellecchia, J.C. Reed, L. Jia

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2006

Language:

english

File:

PDF, 238 KB

english, 2006

18

Diversity of penetration of anti-cancer agents into solid tumours

L. Simpson-Herren, P. E. Noker

Journal:

Cell Proliferation

Year:

1991

Language:

english

File:

PDF, 745 KB

english, 1991

19

Role of Hepatic Tetrahydrofolate in the Species Difference in Methanol Toxicity

Kurt A. Black, Janis T. Eells, Patricia E. Noker, Catherine A. Hawtrey and Thomas R. Tephly

Journal:

Proceedings of the National Academy of Sciences

Year:

1985

Language:

english

File:

PDF, 810 KB

english, 1985

20

A novel and rapid LC/MS/MS assay for bioanalysis of Azurin p28 in serum and its pharmacokinetics in mice

Greg S. Gorman, Lori U. Coward, Lea Freeman, Pat E. Noker, Craig W. Beattie, Lee Jia

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2010

Language:

english

File:

PDF, 226 KB

english, 2010

21

Evaluation of the Safety and Biodistribution of M032, an Attenuated Herpes Simplex Virus Type 1 Expressing hIL-12, After Intracerebral Administration to Aotus Nonhuman Primates

Roth, Justin C., Cassady, Kevin A., Cody, James J., Parker, Jackie N., Price, Kathleen H., Coleman, Jennifer M., Peggins, James O., Noker, Patricia E., Powers, Nicholas W., Grimes, Sheila D., Carroll,

Journal:

Human Gene Therapy Clinical Development

Year:

2014

Language:

english

File:

PDF, 863 KB

english, 2014

22

Toxicology and pharmacokinetics of 1-methyl-d-tryptophan: Absence of toxicity due to saturating absorption

Lee Jia, Karen Schweikart, Joseph Tomaszewski, John G. Page, Patricia E. Noker, Sarah A. Buhrow, Joel M. Reid, Matthew M. Ames, David H. Munn

Journal:

Food and Chemical Toxicology

Year:

2008

Language:

english

File:

PDF, 255 KB

english, 2008

23

Investigations on the basis for the differential toxicity of hexachlorocyclopentadiene administered to rats by various routes

El Dareer, Salah M., Noker, Patricia E., Tillery, Kathleen F., Hill, Donald L.

Journal:

Journal of Toxicology and Environmental Health

Year:

1983

Language:

english

File:

PDF, 753 KB

english, 1983

24

Safety Assessment of AAV2-hGDNF Administered Via Intracerebral Injection in Rats for Treatment of Parkinson's Disease

Terse, Pramod S., Kells, Adrian P., Noker, Patricia, Wright, J. Fraser, Bankiewicz, Krystof S.

Journal:

International Journal of Toxicology

Year:

2020

File:

PDF, 293 KB

2020

25

Comparative Pharmacokinetics of Perfluorobutyrate in Rats, Mice, Monkeys, and Humans and Relevance to Human Exposure via Drinking Water

Chang, S.-C., Das, K., Ehresman, D. J., Ellefson, M. E., Gorman, G. S., Hart, J. A., Noker, P. E., Tan, Y.-M., Lieder, P. H., Lau, C., Olsen, G. W., Butenhoff, J. L.

Journal:

Toxicological Sciences

Year:

2008

Language:

english

File:

PDF, 635 KB

english, 2008

26

Comparison of pharmacokinetic and metabolic profiling among gossypol, apogossypol and apogossypol hexaacetate

Lee Jia, Lori C. Coward, Corenna D. Kerstner-Wood, Ronda L. Cork, Gregory S. Gorman, Patricia E. Noker, Shinichi Kitada, Marrizio Pellecchia, John C. Reed

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2008

Language:

english

File:

PDF, 496 KB

english, 2008

27

Evaluation of hepatic and thyroid responses in male Sprague Dawley rats for up to eighty-four days following seven days of dietary exposure to potassium perfluorooctanesulfonate

Clifford R. Elcombe, Barbara M. Elcombe, John R. Foster, Shu-Ching Chang, David J. Ehresman, Patricia E. Noker, John L. Butenhoff

Journal:

Year:

2012

Language:

english

File:

PDF, 764 KB

english, 2012

28

Lack of a role for formaldehyde in methanol poisoning in the monkey

Kenneth E. McMartin, Gladys Martin-Amat, Patricia E. Noker, Thomas R. Tephly

Journal:

Biochemical Pharmacology

Year:

1979

Language:

english

File:

PDF, 600 KB

english, 1979

29

Variability of tumor response to chemotherapy II. Contribution of tumor heterogeneity

L. Simpson-Herren, P. E. Noker, S. D. Wagoner

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1988

Language:

english

File:

PDF, 1.07 MB

english, 1988

30

The role of methionine in regulating folate-dependent reactions in isolated rat hepatocytes

Ruth E. Billings, Patricia E. Noker, Thomas R. Tephly

Journal:

Archives of Biochemistry and Biophysics

Year:

1981

Language:

english

File:

PDF, 1.05 MB

english, 1981

31

Dose-Related Doxorubicin Effect in an Orthotopic Secondary Lung Cancer Screen

Michael E. Cowen, Randy B. Howard, Patricia E. Noker, Bernard E. Zeligman, David W. Mulvin, Tere Marcell, Michael R. Johnston

Journal:

Journal of Surgical Research

Year:

1994

File:

PDF, 424 KB

1994

32

Treatment strategies in myocardial bridging: a case report

Ihsan Dursun, Muzaffer Bahcivan, Kenan Durna, Firdovsi Ibrahimov, Noker Han Erk, Erdogan Yasar, Mahmut Sahin

Journal:

Cardiovascular Revascularization Medicine

Year:

2006

Language:

english

File:

PDF, 184 KB

english, 2006

33

Interspecies pharmacokinetics and in vitro metabolism of SQ109

Lee Jia, Patricia E Noker, Lori Coward, Gregory S Gorman, Marina Protopopova, Joseph E Tomaszewski

Journal:

British Journal of Pharmacology

Year:

2006

Language:

english

File:

PDF, 220 KB

english, 2006

34

A comparison of the pharmacokinetics of perfluorobutanesulfonate (PFBS) in rats, monkeys, and humans

Geary W. Olsen, Shu-Ching Chang, Patricia E. Noker, Gregory S. Gorman, David J. Ehresman, Paul H. Lieder, John L. Butenhoff

Journal:

Year:

2009

Language:

english

File:

PDF, 909 KB

english, 2009

35

P22—Comparative pharmacokinetics of perfluorohexanesulfonate (PFHxS) in rats and monkeys

Maria Sundström, Shu-Ching Chang, David J. Ehresman, Patricia E. Noker, Geary W. Olsen, Gregory S. Gorman, Jill A. Hart, Trina N. John, Åke Bergman, John L. Butenhoff

Journal:

Reproductive Toxicology

Year:

2012

Language:

english

File:

PDF, 58 KB

english, 2012

36

Metabolism of 14C-labelled sucrose esters of stearic acid in rats

P.E. Noker, T.-H. Lin, D.L. Hill, T. Shigeoka

Journal:

Food and Chemical Toxicology

Year:

1997

Language:

english

File:

PDF, 601 KB

english, 1997

37

Antimitotic agents: structure-activity studies with some pyridine derivatives

Temple, Carroll, Rener, Gregory A., Waud, William R., Noker, Patricia E.

Journal:

Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 580 KB

english, 1992

38

P24—Comparative pharmacokinetics of perfluorooctanesulfonate (PFOS) in rats, mice, and monkeys

Shu-Ching Chang, David J. Ehresman, Patricia E. Noker, Gregory S. Gorman, Jill A. Hart, Trina N. John, Alan Eveland, Jeremy Zitzow, John L. Butenhoff

Journal:

Reproductive Toxicology

Year:

2012

Language:

english

File:

PDF, 58 KB

english, 2012

39

Distribution of Adriamycin in mice bearing mammary adenocarcinoma 16/C

L. Simpson-Herren, P. E. Noker

Journal:

Cell Proliferation

Year:

1991

Language:

english

File:

PDF, 788 KB

english, 1991

40

Identifying the Safety Profile of Ad5.SSTR/TK.RGD, a Novel Infectivity-Enhanced Bicistronic Adenovirus, in Anticipation of a Phase I Clinical Trial in Patients with Recurrent Ovarian Cancer

Matthews, K., Noker, P. E., Tian, B., Grimes, S. D., Fulton, R., Schweikart, K., Harris, R., Aurigemma, R., Wang, M., Barnes, M. N., Siegal, G. P., Hemminki, A., Zinn, K., Curiel, D. T., Alvarez, R. D

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 188 KB

english, 2009

41

Role of hepatic tetrahydrofolate in the species difference in methanol toxicity.

Black, K. A., Eells, J. T., Noker, P. E., Hawtrey, C. A., Tephly, T. R.

Journal:

Proceedings of the National Academy of Sciences

Year:

1985

Language:

english

File:

PDF, 988 KB

english, 1985

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